CRYSTAL STRUCTURE OF A FAB COMPLEX WHITH PLASMODIUM FALCIPARUM MSP1-19 WARNING: Chain C is discontinuous at line 8995. WARNING: Chain F is discontinuous at line 9000. DiscoTope predictions for '1ob1'. Looking only at Chain: C Contact Distance = 10.000 Angstroms Threshold = -7.700 Chain_Id Residue_number Amino_acid Contact_number Propensity_score DiscoTope_score <=B-Identified_B_cell_epitope C 1 ASN 4 1.103 -0.897 <=B C 2 ILE 8 0.865 -3.135 <=B C 3 SER 9 0.278 -4.222 <=B C 4 GLN 14 -1.967 -8.967 C 5 HIS 22 -4.306 -15.306 C 6 GLN 15 -1.000 -8.500 C 7 CYS 21 -2.861 -13.361 C 8 VAL 14 -1.472 -8.472 C 9 LYS 11 -1.411 -6.911 <=B C 10 LYS 14 -2.793 -9.793 C 11 GLN 14 -2.572 -9.572 C 12 CYS 20 -4.561 -14.561 C 13 PRO 17 -2.641 -11.141 C 14 GLN 13 -1.901 -8.401 C 15 ASN 18 -2.916 -11.916 C 16 SER 22 -5.399 -16.399 C 17 GLY 21 -7.330 -17.830 C 18 CYS 24 -6.976 -18.976 C 19 PHE 25 -6.692 -19.192 C 20 ARG 21 -4.388 -14.888 C 21 HIS 17 -3.651 -12.151 C 22 LEU 12 -2.589 -8.589 C 23 ASP 7 -1.070 -4.570 <=B C 24 GLU 12 -1.509 -7.509 <=B C 25 ARG 14 -2.331 -9.331 C 26 GLU 19 -3.386 -12.886 C 27 GLU 16 -3.970 -11.970 C 28 CYS 18 -6.062 -15.062 C 29 LYS 24 -6.697 -18.697 C 30 CYS 25 -5.038 -17.538 C 31 LEU 25 -7.562 -20.062 C 32 LEU 24 -7.822 -19.822 C 33 ASN 20 -2.814 -12.814 C 34 TYR 21 -3.060 -13.560 C 35 LYS 22 -3.103 -14.103 C 36 GLN 17 -1.839 -10.339 C 37 GLU 11 -0.074 -5.574 <=B C 38 GLY 8 0.902 -3.098 <=B C 39 ASP 10 1.207 -3.793 <=B C 40 LYS 16 -1.375 -9.375 C 41 CYS 20 -2.040 -12.040 C 42 VAL 19 -1.910 -11.410 C 43 GLU 16 -1.922 -9.922 C 44 ASN 15 -0.586 -8.086 C 45 PRO 16 1.809 -6.191 <=B C 46 ASN 17 0.996 -7.504 <=B C 47 PRO 22 -0.507 -11.507 C 48 THR 19 -0.756 -10.256 C 49 CYS 19 -1.903 -11.403 C 50 ASN 11 0.521 -4.979 <=B C 51 GLU 10 1.295 -3.705 <=B C 52 ASN 13 -0.559 -7.059 <=B C 53 ASN 20 -4.535 -14.535 C 54 GLY 25 -4.056 -16.556 C 55 GLY 27 -8.244 -21.744 C 56 CYS 29 -12.821 -27.321 C 57 ASP 23 -9.934 -21.434 C 58 ALA 16 -7.540 -15.540 C 59 ASP 19 -8.972 -18.472 C 60 ALA 23 -9.137 -20.637 C 61 LYS 18 -7.588 -16.588 C 62 CYS 23 -7.484 -18.984 C 63 THR 17 -3.678 -12.178 C 64 GLU 15 -1.422 -8.922 C 65 GLU 11 -1.013 -6.513 <=B C 66 ASP 10 0.231 -4.769 <=B C 67 SER 13 0.478 -6.022 <=B C 68 GLY 9 1.485 -3.015 <=B C 69 SER 8 1.371 -2.629 <=B C 70 ASN 8 1.297 -2.703 <=B C 71 GLY 12 1.549 -4.451 <=B C 72 LYS 17 1.115 -7.385 <=B C 73 LYS 20 -0.480 -10.480 C 74 ILE 22 -3.432 -14.432 C 75 THR 19 -7.092 -16.592 C 76 CYS 27 -10.288 -23.788 C 77 GLU 22 -8.896 -19.896 C 78 CYS 24 -9.398 -21.398 C 79 THR 16 -5.761 -13.761 C 80 LYS 14 -5.161 -12.161 C 81 PRO 7 -1.287 -4.787 <=B C 82 ASP 11 -3.119 -8.619 C 83 SER 17 -5.715 -14.215 C 84 TYR 17 -5.764 -14.264 C 85 PRO 18 -6.730 -15.730 C 86 LEU 20 -5.552 -15.552 C 87 PHE 18 -7.667 -16.667 C 88 ASP 19 -7.411 -16.911 C 89 GLY 24 -10.868 -22.868 C 90 ILE 29 -13.112 -27.612 C 91 PHE 29 -11.475 -25.975 C 92 CYS 25 -9.823 -22.323 C 93 SER 21 -5.948 -16.448 C 94 HIS 12 -2.747 -8.747 C 95 HIS 9 -2.185 -6.685 <=B Identified 24 B-Cell epitope residues out of 95 total residues